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糖尿病可以引起一系列的急慢性神经病变,其中远端对称性多发性神经病变(DSP)是最常见的类型。当前DSP治疗主要包括四类:1)针对高血糖、胰岛素抵抗及相关代谢综合征其他组分(如肥胖、血脂紊乱)的药物和生活方式干预;2)针对神经病变已知的病理生理机制的药物治疗;3)缓解神经痛症状的治疗;4)预防神经病变并发症的治疗,如淤积性溃疡、跌倒。
Diabetes can cause a series of acute and chronic neuropathies, of which distal symmetric polyneuropathy (DSP) is the most common type. Currently, there are four main types of DSP treatment: 1) drugs and lifestyle interventions aimed at hyperglycemia, insulin resistance and other metabolic syndrome-related components (such as obesity and dyslipidemia); 2) pathophysiological mechanisms that are known for neuropathy Drug treatment; 3) treatment of neuropathic pain symptoms; and 4) prevention of complications of neuropathy such as stenosed ulcers and falls.