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两肾型Goldblatt高血压大鼠的心脏可见心肌纤维增粗、肌溶小灶、灶性坏死、灶性纤维化和瘢痕形成等病变,冠状动脉出现不同程度的硬化,细动脉纤维样坏死PAS染色呈强阳性。IAE0.5～1.0g/kg灌胃6周对上述心脏损害有一定的保护作用。
The heart of two-kidney Goldblatt hypertensive rats showed thickening of myocardial fibrosis, focal lysis, focal necrosis, focal fibrosis and scar formation. The coronary arteries showed different degrees of sclerosis. PAS staining of fibroid necrosis of fine arteries was observed. Strong positive. IAE 0.5 ~ 1.0g/kg gavage for 6 weeks has a certain protective effect on the above-mentioned cardiac damage.