This work reveals that the addition of periodically distributed stitches to sandwich struc-ture enables a significant reduction of vibration in stop-band and this new functionality is systemat-ically investigated.Firstly,a finite element model which is capable of taking into consideration the three layers of the sandwich as well as the stitches is developed.The diagram of dispersion is calcu-lated by applying Floquet-Bloch theorem to the boundaries of unit cell.With properly chosen prop-erties of stitches,a stop-band for flexural wave is observed.This stop-band is further confirmed by the forced response of a large stitched sandwich panel under point excitation.The level of vibration in the stop-band is significantly reduced.The influence of the stitch rigidity and density on upper and lower limits of stop-band is also examined,which confirms that stitched sandwich can be tuned to mitigate vibration in a certain frequency band with appropriate stitch properties.These investigations have demonstrated the potential application of stitched sandwich in the area of vibration reduction.