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目的:分析癫癎患者服药依从性及其影响因素,探讨提高服药依从性的对策。方法:利用癫癎患者服药依从性调查问卷对确诊为癫癎的246例患者进行调查,以服药依从性好坏分成两组,比较其间各因素的差异,并对服药依从性的影响因素进行Logistic回归分析。结果:246例患者中依从性好组64例,占26%,依从性差组182例,占74%。两组在家庭经济状况、医疗费用支付方式、家长有无癫癎知识、总病程、服药种类、药物不良反应、社会支持之间比较差异存在显著意义(P<0.05),在性别、年龄、职业、文化程度、生活事件、家族史、癫癎种类方面差异则无显著意义(P>0.05)。Logistic回归分析结果,在a=0.05水平上进入回归方程的因素依次为家长有无癫癎知识、药物不良反应、医疗费用支付方式、家庭经济状况和社会支持。结论:癫癎患者服药依从性较差,受多种因素影响,应采取综合措施提高患者服药依从性,从而改善患者疗效和预后。
OBJECTIVE: To analyze medication adherence and its influencing factors in patients with epilepsy and to explore ways to improve adherence to medication. Methods: A total of 246 patients diagnosed as epilepsy were investigated using the medication compliance questionnaire in patients with epilepsy. The patients were divided into two groups according to their medication compliance. The differences among the factors were compared. The influencing factors of medication compliance were analyzed by Logistic regression analysis. Results: Of the 246 patients, 64 were good in compliance group, accounting for 26%, and 182 were in poor compliance group, accounting for 74%. There were significant differences between the two groups in terms of family economic status, payment of medical expenses, knowledge of parents with and without epilepsy, overall course of disease, medication type, adverse drug reactions and social support (P <0.05). There were significant differences in gender, age, occupation , Educational level, life events, family history, epilepsy type no significant difference (P> 0.05). Logistic regression analysis showed that the factors that entered the regression equation at the level of a = 0.05 were parents’ knowledge of epilepsy, adverse drug reactions, payment of medical expenses, family economic status and social support. CONCLUSION: Patients with epilepsy have poor compliance and are influenced by many factors. Comprehensive measures should be taken to improve their compliance with medication so as to improve the efficacy and prognosis of patients.