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目的:评价液基细胞学检测(TCT)结合阴道镜下活检对早期宫颈病变的诊断价值。方法:对1 469例早期宫颈病变进行TCT检测,将诊断意义不明的不典型鳞状细胞(ASCUS)以上病变列为阳性,进一步进行阴道镜下活检,对比分析细胞学诊断与活检结果。结果:TCT标本满意率98.71%,阳性率9.80%,TCT阳性病例阴道镜下活检筛选出CINⅡ、CINⅢ分别为25.69%和54.86%,癌2.08%。结论:TCT技术用于早期宫颈病变筛查能明显提高异常细胞的检出率,敏感性高,配合阴道镜下活检对早期宫颈病变可起到确切的筛选作用。
Objective: To evaluate the diagnostic value of liquid-based cytology (TCT) combined with colposcopy biopsy for early cervical lesions. Methods: A total of 1 469 cases of early cervical lesions were examined by TCT. The above lesions of atypical squamous cell carcinoma (ASCUS) of unknown significance were classified as positive. Colposcopic biopsy was further performed to compare cytological diagnosis and biopsy results. Results: The satisfaction rate of TCT specimens was 98.71%, the positive rate was 9.80%. The colitis CINⅡ and CIN Ⅲ were 25.69% and 54.86%, 2.08% respectively. Conclusion: TCT can be used to detect early cervical lesions can significantly increase the detection rate of abnormal cells, high sensitivity, with colposcopy biopsy for early cervical lesions can play an exact role in screening.