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Henoch-Schonlein紫癜主要发生在儿童,偶尔发生在成人。它的临床特点是腿、臀部出现可触知的紫癜,腹痛、胃肠出血、关节痛和血尿;组织学特征是白细胞碎裂性血管炎,常累及肾脏,以肾小球肾炎为特征;腹痛和胃肠出血偶尔合并肠梗阻和穿孔;继发于冠状血管炎的心肌梗塞也有报导。很少侵犯眼、肺、阴囊、睾丸和神经,后者的损害可从单神经炎到中枢神经系统。不再认为链球菌感染是最常见的致病因素。许多细菌和病毒感染均是抗原的来源。在一些病例中,食物过敏也偶然被证实为病因。据报导促成此综合
Henoch-Schonlein purpura occurs mainly in children, occasionally in adults. Its clinical features include palpable purpura, abdominal pain, gastrointestinal bleeding, joint pain and hematuria in the legs and hips. The histological features are leukocytic disastrous vasculitis, often involving the kidney, characterized by glomerulonephritis; abdominal pain Occasionally combined intestinal obstruction and perforation with gastrointestinal bleeding; myocardial infarction secondary to coronary vasculitis has also been reported. Inflammation rarely affects the eyes, lungs, scrotum, testis and nerves, the latter of which can range from mononeuritis to the central nervous system. Streptococcal infection is no longer considered the most common causative agent. Many bacterial and viral infections are a source of antigens. In some cases, food allergies also occasionally prove to be the cause. It has been reported that this synthesis has been made