用静脉注射用免疫球蛋白(IVIG)进行治疗,有时可能会产生副作用。其临床症状与流感综合征相似,如面部潮红、头痛、发热、寒战、不适、昏厥、恶心、呕吐、肌肉疼痛、腹部痉挛和焦虑。严重反应可能由补体介导,由IVIG自发激活补体系统所引起。IgG聚集物可能是一种引起反应的因素。症状酷似炎症反应,但可能更严重,并包括胸痛、胸闷、呼吸困难、喘鸣、心搏过速,甚至出疹。但真正的过敏症状是对IVIG中的某种成份的超敏反应所引起,例如,IgA或各种稳定剂、防腐剂或者粗制所带有的残渣,由制品污染了感染因子所引起的反应很少。 Treatment with intravenous immunoglobulin (IVIG) can sometimes have side effects. Its clinical symptoms are similar to flu syndromes such as facial flushing, headache, fever, chills, malaise, fainting, nausea, vomiting, muscle aches, abdominal cramps and anxiety. Serious reactions may be mediated by complement, resulting from the spontaneous activation of the complement system by IVIG. IgG aggregates may be a factor that causes the reaction. The symptoms resemble an inflammatory reaction but may be more severe and include chest pain, chest tightness, breathing difficulties, wheezing, tachycardia, and even rash. But the real allergy symptoms are caused by hypersensitivity reactions to certain components of IVIG, such as IgA or various stabilizers, preservatives or crude residues, contaminants caused by contaminants in the product Few.