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实体癌瘤患者在未接受化疗或骨髓未转移前有贫血,多为轻度正细胞、正色素性贫血,血清铁和铁结合力低,骨髓成红细胞前驱物正常,可染铁增加或正常,亦无原始红细胞及对红细胞生成素(EP)反应缺乏,类似肾衰时EP缺乏的正细胞、正色素性贫血。作者为研究肿瘤贫血与EP关系,用敏感的放射免疫法检测81例实体癌瘤患者(乳腺癌34、肺癌15、胃肠肿瘤11及其他21例)血清EP和Hb水平,并与24例缺铁性贫血对照。肿瘤组根据治疗分为未
Solid cancer patients without chemotherapy or bone marrow did not transfer before the anemia, mostly mild positive cells, is pigmented anemia, serum iron and iron binding is low, normal bone marrow erythrocyte precursors, can be increased or normalized with iron, There are also no primitive erythrocytes and a lack of response to erythropoietin (EP), EP-deficient positive cells similar to renal failure, and orthochromatic anemia. In order to study the relationship between tumor anemia and EP, the authors detected the levels of serum EP and Hb in 81 patients with solid carcinoma (breast cancer 34, lung cancer 15, gastrointestinal cancer 11 and other 21) by radioimmunoassay and compared with 24 patients Iron anemia control. The tumor group was divided according to the treatment