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ｐ5 3、ｐ2 1是两种相关癌基因〔1〕,它们的突变失活或突变激活 ,在肿瘤的演进过程中有着重要的意义 ,但对胆囊癌ｐ5 3、ｐ2 1蛋白检测的资料甚少 ,本文旨在探讨其在胆囊癌发生发展过程中的生物学意义。1 材料与方法1.1 标本来源 收集本院 1995年 1月～ 1999年 6月外科手术
P5 3 and p21 are two related oncogenes [1]. Their mutational inactivation or mutation activation is of great significance in the evolution of tumors. However, little information is available on the detection of p53 and p21 protein in gallbladder cancer. This article aims to explore its biological significance in the development of gallbladder cancer. 1 Materials and Methods 1.1 Specimen Sources Collection This hospital January 1995 to June 1999 Surgery