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目的 :通过统计和分析中国西部的西安西京医院及重庆西南医院诊治的皮肤恶性肿瘤的基本临床资料 ,为了解中国西部皮肤恶性肿瘤的发病情况和变化趋势提供线索。方法 :收集、统计和分析两所医院 1981至 2 0 0 0年经病理确诊的皮肤恶性肿瘤的临床资料。结果 :(1)共纳入皮肤恶性肿瘤患者 190 5例 ,其中鳞状细胞癌 5 6 0例(2 9.4 % )、基底细胞癌 5 34例 (2 8.0 % )、皮肤恶性黑素瘤 30 5例 (16 .0 % )。 (2 ) 190 5例皮肤恶性肿瘤的患者中 ,80年代 5 91例 ,90年代 1314例 ,占同期由于各种疾病行病理活检患者总数的比例分别为 0 .34%及 0 .5 8% ;此 2 0年间因各种疾病行病理活检的患者总数年均增长 1.6 % ,而皮肤恶性肿瘤患者活检数年均增长 3.5 % ,其中皮肤恶性黑素瘤年增长 3.9%。 (3) 30 5例皮肤恶性黑素瘤中 ,肢端恶性黑素瘤占 6 3.3%。与非肢端恶性黑素瘤相比 ,肢端恶性黑素瘤患者年龄大、外伤比例高、男性多见。 (4 ) 30 5例皮肤恶性黑素瘤中 ,6 4例 (2 1% )原发部位有明确外伤史 ,4 7例 (15 .4 % )源于先天性小痣。结论 :中国皮肤恶性肿瘤的构成比以及发生部位、年龄等与白色人种有很大差异。2 0年来 ,中国皮肤恶性肿瘤特别是皮肤恶性黑素瘤有明显增加的趋势。外伤、先天性小痣是中国皮肤恶性黑素瘤的
OBJECTIVE: To provide clues for understanding the incidence and trend of skin malignancies in western China by means of statistical analysis of the basic clinical data of skin malignancies diagnosed and treated in Xi’an Xijing Hospital and Chongqing Southwest Hospital in western China. Methods: The clinical data of pathologically confirmed skin malignancies from 1981 to 2000 in two hospitals were collected, analyzed and analyzed. Results: (1) A total of 1905 patients with malignant tumors of the skin were enrolled in this study. Of them, squamous cell carcinoma was 56.0 (2.94%), basal cell carcinoma was 5 34 (28.0%), and skin malignant melanoma (16.0%). (2) Of 1905 patients with malignant skin tumors, 591 cases in the 80s and 1314 cases in the 90s accounted for 0.34% and 0.58% of the total number of pathological biopsies due to various diseases in the same period. The total number of patients biopsied by various diseases during the 20 years increased by an average of 1.6% annually, while the number of skin cancer patients with biopsies increased by 3.5% over the years, with the annual increase of skin malignant melanoma by 3.9%. (3) Acromegaly of malignant melanoma in 30 5 cases accounted for 6 3.3%. Compared with non-extremity malignant melanoma, patients with extremity malignant melanoma are older and have a higher proportion of trauma, more common in males. (4) Of the 305 cases with cutaneous malignant melanoma, 64 cases (21%) had a clear history of trauma and 47 (15.4%) had congenital malformations. Conclusion: The constitutional ratio of malignant tumors in China and the location, age, and white race are quite different. In the past 20 years, Chinese skin malignancies, especially the skin malignant melanoma, have a clear trend of increase. Trauma, congenital small nevus is Chinese skin malignant melanoma