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目的比较不同的手术切缘对肝癌患者术后复发及生存的影响。方法回顾性分析2003年至2005年在新疆维吾尔自治区人民医院行手术治疗的初治的肝癌患者,共纳入64例,根据切缘大小分为两组并给予随防,比较两组的无瘤生存期和总生存期。结果宽切缘组患者平均无瘤生存期为35.5个月,平均总生存期为42.0个月;窄切缘组患者平均无瘤生存期为28.8个月,平均总生存期为37.5个月,两组无瘤生存期和总生存期比较差异均有统计学意义(P<0.05)。结论肿瘤切缘>1 cm可延长肝癌患者术后无瘤生存期和总生存期。
Objective To compare the effects of different surgical margins on the recurrence and survival of patients with liver cancer. Methods A retrospective analysis was performed on 64 untreated patients with hepatocellular carcinoma who underwent surgery in People’s Hospital of Xinjiang Uigur Autonomous Region from 2003 to 2005. A total of 64 patients were enrolled and divided into two groups according to the size of the margin. Period and overall survival. Results The average tumor-free survival was 35.5 months in the wide margin group and 42.0 months in the margin-wide margin group. The mean tumor-free survival was 28.8 months in the narrow-margin group, with a mean overall survival of 37.5 months. The tumor-free survival and overall survival were significantly different (P <0.05). Conclusion The tumor margin> 1 cm can prolong the tumor-free survival and overall survival of patients with liver cancer.