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目的探究肾动脉狭窄患者经过肾动脉支架手术后血浆炎性因子C—反应蛋白(CRP)、白介素(IL-6)的水平与临床预后的关系。方法整群选取2013年12月—2016年3月在北京军区总医院、济宁市第一人民医院等院接受治疗的肾动脉狭窄患者280例,其中198例患者接受了肾动脉支架手术,其余的82例患者没有接受该手术,通过对术前术后以及未接受手术患者的血浆中CRP和IL-6的因子水平测量进行对比分析。结果经过对因子水平的测定后,患者在手术后的炎性因子水平均普遍升高,在1个月后,对手术后患者检测中发现有45例患者体内的炎性因子水平增加。结论通过血浆炎性因子水平能够对患者在肾动脉支架手术后进行临床预后,可以帮助患者早确诊早治疗术后的并发症,改善患者的健康。
Objective To investigate the relationship between the levels of inflammatory cytokines C-reactive protein (CRP), interleukin (IL-6) and clinical prognosis in patients with renal artery stenosis after renal artery stenting. Methods A total of 280 patients with renal artery stenosis treated in the Beijing Military Region General Hospital and the First People’s Hospital of Jining City from December 2013 to March 2016 were selected. Among them, 198 patients underwent renal artery stenting and the rest Eighty-two patients were excluded from the procedure and were analyzed by comparing the plasma levels of CRP and IL-6 in preoperative and postoperative patients. Results After the determination of the level of the factors, the level of inflammatory cytokines in the patients after surgery generally increased. One month later, 45 patients were found to have increased levels of inflammatory cytokines in postoperative patients. Conclusion The clinical outcome of patients with renal artery stenting through plasma levels of inflammatory cytokines can help patients diagnose early complications and improve their health.