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目的分析孟鲁司特治疗成人哮喘急性发作的临床疗效。方法 70例成人哮喘急性发作患者,将其随机分为观察组与对照组,各35例。对照组给予常规治疗,主要包括抗炎、吸氧、平喘、解痉等,观察组在对照组基础上加用孟鲁司特治疗,比较两组患者的临床疗效。结果观察组患者的哮鸣音消失时间、咳痰消失时间、哮喘消失时间均少于对照组,差异有统计学意义(P<0.05);观察组总有效率为94.3%,对照组总有效率为68.6%,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论孟鲁司特治疗成人哮喘急性发作的临床疗效显著,可有效改善患者的临床症状,值得在临床上进一步推广。
Objective To analyze the clinical efficacy of montelukast in the treatment of acute asthma in adults. Methods Seventy patients with acute exacerbation of asthma were randomly divided into observation group and control group with 35 cases each. The control group was given routine treatment, including anti-inflammatory, oxygen, asthma, antispasmodic, etc. The observation group was treated with montelukast on the basis of the control group, and the clinical efficacy was compared between the two groups. Results The disappearance time of wheeze, disappearance of expectoration and disappearance of asthma in the observation group were all less than those in the control group (P <0.05). The total effective rate in the observation group was 94.3%. The total effective rate Was 68.6%. The total effective rate in the observation group was higher than that in the control group, the difference was statistically significant (P <0.05). Conclusion The clinical efficacy of montelukast in the treatment of acute exacerbation of adult asthma is significant, which can effectively improve the clinical symptoms of patients and deserve further promotion in clinic.