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目的研究肝炎综合征患者血清总汁酸(TBA)的表达。方法选择84例肝炎综合征患者与20例非肝胆疾病患者作为对照组,测定他们血清总胆汁酸(TBA)和谷丙转氨酶、总胆红素的表达水平。结果对照组的TBA表达明显低于患者组的TBA,两组比较差异有统计学意义(P<0.01),而与谷丙转氨酶(GPTP<0.01)总胆红素(TB ILP<0.01)有显著相关性且TBA的阳性率高于谷丙转氨酶(GPT)的阳性率(P<0.05)。结论血清TBA的表达在反映肝功能报伤方面是一个灵敏的指标,对肝炎综合征患者的早期诊断治疗和预后有重要意义。
Objective To study the expression of serum total acid (TBA) in patients with hepatitis syndrome. Methods Eighty-four patients with hepatitis syndrome and 20 patients with non-hepatobiliary disease were selected as control group, and their serum levels of total bile acid (TBA), alanine aminotransferase (ALT) and total bilirubin were measured. Results The TBA expression in the control group was significantly lower than that in the patient group (P <0.01), while the total bilirubin (GPI <0.01) was significantly lower than that in the control group The positive rate of TBA was higher than that of GPT (P <0.05). Conclusion The expression of serum TBA is a sensitive index in reflecting the damage of liver function. It is of great significance for the early diagnosis, treatment and prognosis of patients with hepatitis syndrome.