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探讨血小板输注的适应症及效果,对35例次(26例病人)因不同病因致血小板减少而作血小板输注的患儿进行临床研究。测定输注前及输注后24小时血小板计数。计算输后血小板增值、回升率及纠正计数指数(CCI)。比较输注前后出血症状,评价疗效。结果表明,输注后出血症状改善者24/28例次(85.7%)。输后24小时血小板增值为(28.94±10.97)×109/L(X±S);回升率为57.98±18.51%,达到正常预期值(60%)者16例次(45.7%);CCI为(7.00±2.15)×109/L,>7.5×109/L者18例次(51.4%)。因此,血小板输注可预防和治疗血小板减少所致的出血。评价其效果除了观察血小板增值、回升率及CCI外,临床出血症状的明显改善是最直接最实际的准则
To investigate the indications and effects of platelet transfusion, 35 cases (26 patients) due to different causes of thrombocytopenia for platelet transfusion in children for clinical study. The platelet counts were measured 24 hours before and after infusion. Post-transfusion thrombocytopenia, rate of recovery, and Correction Index (CCI) were calculated. Compare the bleeding symptoms before and after infusion, evaluate the curative effect. The results showed that 24/28 patients (85.7%) had improved bleeding after infusion. (28.94 ± 10.97) × 109 / L (X ± S) at 24 hours after transfusion; the rate of recovery was 57.98 ± 18.51% and the normal expected value (60%) was 16 cases (45.7%); CCI was ( 7.00 ± 2.15) × 109 / L and> 7.5 × 109 / L in 18 cases (51.4%). Therefore, platelet transfusion prevents and treats bleeding due to thrombocytopenia. Evaluation of its effect In addition to observation of thrombocytopenia, the rate of recovery and CCI, the obvious improvement of clinical symptoms of bleeding is the most direct and practical guidelines