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一般认为,二价铬的化合物是无毒的,三价铬具有生理作用,是人体必需的微量元素,参与正常糖代谢过程,对胰岛素的利用有促进作用.而六价铬有毒理作用,铬酸盐或六价铬化合物能刺激并对所有组织有毒,六价铬化合物与致癌可能有一定关系.为了解六价铬在体内的吸收、分布和排出,了解铬在体内清除情况,为进一步研究铬的毒理作用提供依据,用放射性铬进行了本实验研究.
It is generally believed that the compounds of bivalent chromium are non-toxic and trivalent chromium has a physiological effect and is an essential trace element for the body and participates in the process of normal glucose metabolism, promoting the use of insulin, while hexavalent chromium has toxicological effects, Chromate or hexavalent chromium compounds can stimulate and be toxic to all tissues, and hexavalent chromium compounds may have something to do with carcinogenesis. To understand the absorption, distribution and excretion of hexavalent chromium in the body, to understand chromium removal in vivo, To study the toxic effects of chromium provides the basis for the experimental study of radioactive chromium.