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目的:探讨保妇康栓局部使用治疗HPV感染的有效性。方法:选择2011年11月~2012年5月我院宫颈病门诊确诊宫颈HPV感染的患者共160例。将入组病人分成治疗组(A)、对照组(B)2组,A组给予保妇康栓治疗,B组拒绝接受任何治疗的人群,2组均于8个月后复查HPV高危型DNA检测及分型。结果:A组转阴率为75%。总有效率为82.3%;B组转阴率为40.6%,总有效率51.5%,两者比较差异具有显著性(P>0.05)。结论:保妇康栓能有效抑制HPV病毒,降低了HPV感染患者向宫颈癌进展的发生。此药物疗效确切,使用方法简单易行,经济实用,易于被患者接受,值得临床推广和应用。
Objective: To investigate the effectiveness of Baofukang suppository in the treatment of HPV infection. Methods: From November 2011 to May 2012, 160 cases of cervical HPV infection were diagnosed in our cervical disease clinic. The patients were divided into treatment group (A), control group (B) 2 group, A group given Baofukang suppository, B group refused to receive any treatment of the crowd, two groups were 8 months after the review of HPV high-risk DNA Detection and typing. Results: The negative conversion rate of group A was 75%. The total effective rate was 82.3%. The negative conversion rate in group B was 40.6% and the total effective rate was 51.5%. There was significant difference between the two groups (P> 0.05). Conclusion: Baofukang suppository can effectively inhibit HPV virus and reduce the incidence of cervical cancer in patients with HPV infection. The drug is effective, the use of simple, economical and practical, easy to be accepted by patients, it is worth clinical promotion and application.