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目的 观察SARS患者血清干扰素 -2α(IFN --2α)含量变化。方法 用放射免疫法检测了 66例SARS患者血清IFN-2α含量 ,并与正常对照组作比较。结果 SARS组进展期患者IFN -2α含量明显高于对照组 ,重型SARS患者血清IFN -2α含量要么较高 ,要么较低。结论 患者血清IFN -2α含量变化提示细胞免疫参与了机体的免疫反应 ,重症SARS患者IFN -2α含量变化反映了患者的免疫机能状况差异
Objective To observe the changes of serum interferon - 2α (IFN - α) in SARS patients. Methods Radioimmunoassay was used to detect the serum levels of IFN-2α in 66 SARS patients and compared with the normal control group. Results The IFN-α level in patients with advanced SARS was significantly higher than that in the control group. The serum IFN-α levels in patients with severe SARS were either higher or lower. Conclusions The change of serum IFN-α level in patients indicates that cellular immunity is involved in the immune response. The change of IFN-α content in patients with severe SARS reflects the differences in immune function status