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巴戟天属助阳药,有补肾助阳、散风祛寒湿之功效。我们在临床上用巴戟天30g、山萸肉30g 治愈2例呈典型柯兴氏症候群的儿童肾病综合征。因此设想巴戟天可能有类似皮质激素样作用,故进行了以下试验。所用正品巴戟天为 Morinda officinalis How,剂型为巴戟天温浸剂及50%乙醇提取液。一、巴戟天对未成年小白鼠胸腺的影响用未成年小白鼠,按 ACTH 生物活性检定法作试验,共用药4天,结果证明:巴戟天温浸剂64g/kg/日、80g/kg/日口服,及巴戟天50%乙醇提取液60g/kg/日口服,其胸腺萎缩非常显著(P 值分别为 P<
Bajitian is a medicine for Yang, which has the effect of replenishing kidney, promoting yang and dispersing wind and dampness. We used clinical Morinda officinalis 30g and Hawthorn meat 30g to cure 2 children with classic Cushing’s syndrome nephrotic syndrome. Therefore, it is assumed that Morinda officinalis may have a corticosteroid-like effect, so the following tests were conducted. The authentic Morinda officinalis How is used in the Morinda officinalis How, and the Morinda officinalis How and dosage form is the Morinda officinalis How and the 50% ethanol extract. I. Effect of Morinda officinalis on the thymus of underage mice Rats were tested on the ACTH biological activity test using an underage rat. The drug was used for 4 days. The results showed that the Morinda officinalis extract was 64g/kg/day, 80g/day. Kg/day orally, and Morinda officinalis 50% ethanol extract 60g/kg/day orally, the thymus atrophy is very significant (P values are P<