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目的:探讨逍遥丸联合文拉法辛治疗脑卒中后抑郁的疗效。方法 :将80例PSD患者随机分为治疗组和对照组各40例,对照组予文拉法辛及谷维素治疗,治疗组口服逍遥丸及文拉法辛,其余常规治疗相同。比较两组治疗前后汉密尔顿抑郁评分(HAMD)、斯堪的纳维亚卒中评分(SSS)及临床疗效。结果 :治疗后,治疗组的总有效率明显高于对照组(P<0.05),HAMD评分和SSS评分均明显低于对照组(均P<0.05)。结论 :逍遥丸联合文拉法辛可明显改善PSD患者的抑郁症状,同时能促进其神经功能的恢复。
Objective: To investigate the efficacy of Xiaoyao Pill combined with venlafaxine in the treatment of post-stroke depression. Methods: Eighty patients with PSD were randomly divided into treatment group (40 cases) and control group (40 cases). The control group was treated with venlafaxine and oryzanol, and the treatment group was given oral Xiaofu Wan and venlafaxine. The rest of the routine treatment was the same. The Hamilton Depression Rating (HAMD), Scandinavian Stroke Scale (SSS) and clinical efficacy were compared between the two groups before and after treatment. Results: After treatment, the total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). HAMD score and SSS score were significantly lower than those of the control group (all P <0.05). Conclusion: Xiaoyao pill combined with venlafaxine can significantly improve the depression symptoms of PSD patients, at the same time can promote the recovery of nerve function.