论文部分内容阅读
随着越来越多的实验证实反复多次痫性发作可产生神经系统的积累损伤,以及临床影像和神经心理学检查的进展,癫痫神经元保护治疗的概念开始引起人们的注意。大量动物实验证实,许多抗癫痫药物在抗惊厥同时,还具有一定的神经保护作用,但临床上要精确评估其对癫痫神经元的保护作用非常困难,除缺少敏感特异的监测指标外,还存在遗传因素、痫性发作持续时间和干预措施开始时间等影响因素。
As more and more experiments confirm that repeated episodes of epileptic seizures can lead to the accumulation of nervous system damage, as well as the progress of clinical imaging and neuropsychological tests, the concept of epileptic neuronal protection therapy has drawn people’s attention. A large number of animal experiments confirmed that many anti-epileptic drugs in anticonvulsant at the same time, it also has some neuroprotective effect, but the clinical precise assessment of its protective effect on epileptic neurons is very difficult, in addition to the lack of sensitive and specific monitoring indicators, there Genetic factors, the duration of epileptic seizures and the starting time of interventions and other influencing factors.