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将100例肺结核病患者,按照随机分组的原则分为观察组和对照组,对照组患者运用抗痨药物进行治疗;观察组则在对照组基础上使用喹诺酮类药物进行治疗。通过对两组患者的病情发展情况进行统计观察,分析两组治疗方法在治疗效果和治疗过程中存在的不良反应发生情况的不同。对照组治疗总有效率为78.0%,痰菌转阴率为73.1%;观察组治疗总有效率为98.0%,痰菌转阴率为88.0%。观察组的总有效率和痰菌转阴率均明显高于对照组,二者差异具有明显的统计学意义(P<0.05)。两组治疗方法在治疗过程中均未出现明显的不良反应。氟喹诺酮类药物在治疗肺结核上的疗效肯定,优于单纯的抗痨治疗,不良反应较少,方便使用,值得在临床上推广使用。
One hundred cases of pulmonary tuberculosis patients were divided into observation group and control group according to the principle of randomization. Patients in control group were treated with anti-tuberculosis drugs. The observation group was treated with quinolone on the basis of control group. By statistical analysis of the two groups of patients with the development of the disease, analysis of two groups of treatment methods in the treatment effect and the existence of adverse reactions in the course of the situation is different. In the control group, the total effective rate was 78.0% and the sputum negative conversion rate was 73.1%. The total effective rate was 98.0% in the observation group and 88.0% in the sputum. The total effective rate of observation group and sputum negative conversion rate were significantly higher than the control group, the difference was statistically significant (P <0.05). Two groups of treatment in the course of treatment did not appear obvious adverse reactions. Fluoroquinolones in the treatment of pulmonary tuberculosis certainly positive, better than simple anti-tuberculosis treatment, fewer adverse reactions, easy to use, it is worth promoting the clinical use.