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目的:分析多发伤后全身炎症反应综合征(SIRS)的发生率和病死率以及SIRS与休克的关系。方法:多发伤412例,分为SIRS组和非SIRS组,比较两组的病死率,并进行SIRS评分以及按休克严重程度分组,分析多发伤后SIRS与休克的关系及多发伤病死率与SIRS评分的关系结果:多发伤后SIRS发生率为87.6%,SIRS组病死率明显高于非SIRS组(P<0.05)。随休克严重程度的增加,SIRS发生率明显升高(r=1,P<0.01)。同时多发伤病死率也随着SIRS分值的增加而增高(P<0.05)。结论:大多数多发伤患者发生了SIRS,发生SIRS后病死率较高。SIRS的发生率与休克严重程度呈正相关。积极抗休克治疗及早期进行脏器功能支持应是防治SIRS的有力的措施。
OBJECTIVE: To analyze the incidence and mortality of systemic inflammatory response syndrome (SIRS) after multiple trauma and the relationship between SIRS and shock. Methods: A total of 412 cases of multiple trauma were divided into SIRS group and non-SIRS group. The mortality of the two groups was compared. The SIRS score and the severity of shock were also divided into groups. The relationship between SIRS and shock, The results of SIRS score showed that the incidence of SIRS after multiple trauma was 87.6%, and the mortality of SIRS group was significantly higher than that of non-SIRS group (P <0.05). With the increase of the severity of shock, the incidence of SIRS increased significantly (r = 1, P <0.01). Multiple injuries at the same time also increased with the SIRS scores increased (P <0.05). Conclusions: SIRS occurred in most patients with multiple traumas, with a higher case fatality rate after SIRS. The incidence of SIRS was positively correlated with the severity of shock. Active anti-shock treatment and early support of organ function should be a powerful measure to prevent and treat SIRS.