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疼痛治疗分为药物治疗和非药物治疗。药物治疗包括非甾体类抗炎药、阿司匹林和扑热息痛等非阿片类镇痛药、阿片类镇痛药、“辅助”药物如抗抑郁药阿米替林和抗惊厥药卡马西平等。非药物治疗包括神经刺激疗法、神经阻滞疗法、外科手术、物理治疗、心理-行为疗法等。本文介绍我们临床上常见的颞下颌关节骨关节炎、肌筋膜疼痛、神经病理性疼痛(非典型牙痛、治疗后神经痛、三叉神经痛)及复合性局部疼痛综合征的主要临床用药和理论基础,如非甾体类抗炎药特异性COX-2抑制剂、改善骨关节炎症状和关节结构的药物硫酸氨基葡萄糖、阿片类药物曲马多、三环类抗抑郁药阿米替林、新一代抗惊厥药加巴喷丁等。
Pain treatment is divided into medical treatment and non-medical treatment. Drug treatment includes non-opioid analgesics such as non-steroidal anti-inflammatory drugs, aspirin and paracetamol, opioid analgesics, and “auxiliary” drugs such as antimitensant amitriptyline and anticonvulsant carbamazepine . Nonpharmacological treatments include neurostimulation therapy, nerve block therapy, surgery, physical therapy, psycho-behavioral therapy and the like. This article presents the main clinical and theoretical basis of our clinical trials of temporomandibular joint osteoarthritis, myofascial pain, neuropathic pain (atypical toothache, post-treatment neuralgia, trigeminal neuralgia) and complex local pain syndrome , Such as non-steroidal anti-inflammatory drug-specific COX-2 inhibitors, drugs that improve symptoms and joint structures of osteoarthritis Glucosamine Sulfate, the opioid tramadol, the tricyclic antidepressant amitriptyline, Generation of anticonvulsant gabapentin and so on.