论文部分内容阅读
在人体肿瘤发生上,染色体参与已非偶然现象.但人们对于恶性淋巴瘤染色体形态的了解却不多.七十年代初染色体技术发展以来,观察了淋巴瘤染色体的变化,以探讨此类变化的标记特征.与白血病患者检查染色体主要是取骨髓不同,淋巴瘤患者检查染色体则取淋巴结、脾、骨髓和外周淋巴细胞,以及渗出物做短期(2—72时)培养.少数用传代的细胞系.培养的缺点是,一方面新生的细胞很快被正常细胞控制;另一方面试管内培养可产生染色体核型改变,易导致错误的识别.
Chromosome participation has been a non-accidental phenomenon in the development of human tumors, but people do not know much about the morphology of malignant lymphoma chromosomes. Since the development of chromosome technology in the early 1970s, the changes of lymphoma chromosomes have been observed to explore such changes Marker characteristics.And with leukemia patients to check the chromosome is mainly taken from the bone marrow, lymphoma patients to check the chromosomes are taken lymph nodes, spleen, bone marrow and peripheral lymphocytes, and exudate for short-term (2-72 hours) culture.A few use of passaged cells Department of culture is the disadvantage that, on the one hand, newborn cells are quickly controlled by normal cells; on the other hand, in vitro culture can produce changes in karyotype, easily lead to false recognition.