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p53基因是目前发现的与人类肿瘤发病相关性最大的抑癌基因之一。p53基因的点突变、缺失及灭活在肿瘤的发生和进展过程中起着关键性的作用。随着各项研究的不断进展以及高新检测技术的出现,p53在肿瘤发病早期诊断中的价值得到进一步的肯定,同时利用p53进行基因治疗的研究也逐渐?
p53 gene is currently one of the most tumor suppressor genes found in human tumors. Point mutation, deletion and inactivation of p53 gene play a key role in the process of tumorigenesis and progression. With the continuous development of various research and the emergence of high-tech detection technology, the value of p53 in the early diagnosis of cancer is further affirmed, and the research of gene therapy using p53 is also gradual?