目的：为了解精纯抗栓酶对脑梗死患者近期疗效和血凝及纤溶系统指标的影响。方法：设精纯抗栓酶治疗组３１例和常规治疗对照组３０例，治疗７ｄ后观察其疗效及血凝、纤溶系统指标。结果：治疗组和对照组痊愈率分别为４５２％和３３％（Ｐ＜００１），显效率分别为８７９％和４０４％（Ｐ＜００１），凝血酶时间（ｔＴ）、凝血酶原时间（ｔＰ）、激活的部分凝血活酶时间（（ｔＫＰＴ）较对照组延长（Ｐ＜００１），纤维蛋白原（ＦＧ）亦显著降低（Ｐ＜００１）、Ｄ二聚体（ＤＤ）则显著高于对照组和治疗前（Ｐ＜００１）。结论：精纯抗栓酶起作用快，疗效较高，能明显改善神经功能，具有明显抗凝、降纤和抗凝血酶作用。 Objective: To understand the effect of antithrombotic enzyme on short-term curative effect and indexes of hemagglutination and fibrinolysis in patients with cerebral infarction. Methods: Thirty-one patients in the group treated with antithrombotic enzyme and 30 patients in the control group were treated with anti-thrombolytic enzyme. The therapeutic effect and indexes of hemagglutination and fibrinolytic system were observed after 7 days of treatment. Results: The cure rates of treatment group and control group were 452% and 33% (P <001) respectively, and the effective rates were 879% and 404% respectively (P00101) Compared with control group, tT, tP and tKPT prolonged (P <001) and fibrinogen (FG) decreased significantly (P0.01) 01), D  dimer (D  D) was significantly higher than the control group and before treatment (P <0  01) .Conclusion: Purified antithrombotic enzyme has a rapid effect, high efficacy, can significantly improve the nerve Function, with significant anticoagulation, fibrinolysis and antithrombin effect.