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目的 :研究和观察脉络宁对老年人心血管疾病治疗前后肝功能 (谷丙酶 ALT、谷草酶 AST、γ转肽酶、γ- GT)损害进行评估。方法 :对 1 0 2例老年人在应用脉络宁 2 0 ml前后分别进行肝功能检测 ,详细记录肝功能数值变化 ,并进行统计学有效处理。结果 :1 0 2例患者应用脉络宁后肝功能损害率为 1 2 .7%。其中ALT、AST、γ- GT的异常率分别为 6 .86 %、4.9%、 8.82 %。 95 %置信区间分别为 0 .41 ;1 3.31、 0 .75 ;9.0 9、 3.31 ;1 4.33,脉络宁对ALT、AST、γ- GT数值变化分析显示 :ALT相差显著 ( P<0 .0 1 ) ,AST相差非常显著 ( P<0 .0 5 ) ,γ- GT相差不显著 ( P>0 .0 5 )。结论 :脉络宁对老年人肝功能有一定程度的损害
Objective: To study and observe the effect of Mailuoning on the liver function (ALT, AST, γ-GT) of elderly patients with cardiovascular diseases before and after treatment. Methods: A total of 102 elderly patients were treated with Mailuoning 20 ml before and after liver function tests were recorded in detail the changes in liver function values, and statistically effective treatment. Results: The rate of liver damage was 102.7% after 102 cases were treated with Mailuoning. The abnormal rates of ALT, AST and γ-GT were respectively 6.86%, 4.9% and 8.82%. 95% confidence intervals were 0.41; 1.31, 0.75; 9.09, 3.31; 1.33, respectively. Analysis of the changes of ALT, AST and γ-GT in Mailuoning showed that the difference of ALT was significant (P <0.01) ), The difference of AST was very significant (P <0.05), and the difference of γ-GT was not significant (P> 0.05). Conclusion: Mailuoning has some damage to the liver function of the elderly