论文部分内容阅读
青籐碱(Sinomenine)系自防己科植物Sinomeninum acutum Rehd et Wils的根及茎提得的生物碱。我们前文(1960)曾报告其镇痛及消炎作用,本文对其毒性及一般药理进行以下观察: 青籐碱对小白鼠口服半数致死量为580±51毫克/公斤;大白鼠一次口服694毫克/公斤无不良反应;
Sinomenine is an alkaloid derived from the roots and stems of Sinomeninum acutum Rehd et Wils. Our previous article (1960) reported its analgesic and anti-inflammatory effects. The following observations were made on the toxicity and general pharmacology of this article: The oral lethal dose of sinomenine to mice was 580±51 mg/kg; the rats received oral 694 mg once daily. Kilograms no adverse reactions;