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原发性胆汁性肝硬化（ＰＢＣ）、原发性硬化性胆管炎（ＰＳＣ）是以肝内胆汁淤积为特征的疾病，预后较差，往往需要肝移植。近来，熊去氧胆酸（ＵＤＣＡ）在治疗ＰＢＣ、ＰＳＣ等胆汁淤积疾病中的作用越来越受到重视，并且有报道在肝移植病人中应用有明显疗效。本文对ＵＤＣＡ
Primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) is characterized by intrahepatic cholestasis of the disease, the prognosis is poor, often require liver transplantation. Recently, the role of ursodeoxycholic acid (UDCA) in the treatment of cholestatic diseases such as PBC and PSC is gaining more and more attention. It has been reported that UDCA has obvious curative effect in liver transplantation patients. This article on UDCA