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目的 分析胃肠道神经鞘瘤的发病概况并探讨其诊治方法。方法 对12 例胃肠道神经鞘瘤进行回顾性分析并文献复习。结果 术前确诊仅1 例,手术切除10 例,术中活检2 例;良性5 例,2 年内死于伴发病2例,存活已> 2 年3 例;恶性4 例,1 年及3 年内死亡各为3 例及1 例;恶变倾向3 例,2 年内死亡1 例,已存活> 6年2 例。结论 胃肠道神经鞘瘤术前诊断困难,确诊靠病理,免疫组化检查有助于与平滑肌瘤鉴别。良性者可行局部切除,恶性或恶性倾向者应行根治性切除,术中快速病理切片有助于决定手术方式。
Objective To analyze the incidence of gastrointestinal schwannomas and discuss the diagnosis and treatment methods. Methods 12 cases of gastrointestinal schwannoma were retrospectively analyzed and reviewed in the literature. Results Only 1 case was diagnosed before surgery. 10 cases were surgically removed and 2 cases were biopsy. 5 cases were benign. 2 cases died of comorbidity within 2 years and 3 cases survived 2 years; 4 cases were malignant and died within 1 year and 3 years. There were 3 cases and 1 case respectively; 3 cases had malignancy, 1 case died within 2 years, and 2 cases survived >6 years. Conclusions Preoperative diagnosis of gastrointestinal schwannomas is difficult. The diagnosis depends on pathology. Immunohistochemical examination is helpful in distinguishing from leiomyomas. Benign resection can be feasible, malignant or malignant tendencies should be radical resection, intraoperative rapid pathological sections help determine the surgical approach.