论文部分内容阅读
鼻腔、鼻窦内翻性乳头状瘤 (NIP)组织中某些人乳头状瘤病毒 (HPV)、EB病毒、P53基因表达显著增强 ,恶变率较高。刀豆素 A(Con A)、神经酰胺酶预处理花生凝集素 (NA-PNA)免疫组化表明 NIP恶变鳞癌中为强阳性。这些生物学特性为定义 NIP为癌前病变提供依据。John根据内窥镜检查肿瘤在鼻腔的范围 ,和 CT所见提出了探讨能代表疾病严重程度的统一的疾病分期标准。以利于客观地评价不同的手术方法对于 NIP的疗效 ,及不同的医生所采用的相同的方法的效果。强调术后全部组织做病理检查、术后长期随访非常重要
Some human papillomavirus (HPV), Epstein-Barr virus and P53 gene expression in nasal and sinus inverted papilloma (NIP) tissues were significantly increased, and the malignant transformation rate was higher. Immunohistochemistry of concanavalin A (Con A) and neuramidase preconditioning peanut agglutinin (NA-PNA) showed strong positive staining in malignant squamous cell carcinoma of the NIP. These biological properties provide the basis for the definition of NIP for precancerous lesions. John based on endoscopic examination of the tumor in the nasal cavity, and CT seeks to explore uniform disease staging criteria that represent the severity of the disease. So as to objectively evaluate the curative effect of different surgical methods on NIP and the effect of the same method adopted by different doctors. Emphasize postoperative pathological examination of all tissues, long-term follow-up is very important