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目的:观察急性苯丙胺类药物中毒的临床表现特点及治疗效果。方法:回顾性分析2010年1月至2012年6月急诊科诊治的急性苯丙胺类药物中毒患者88例的临床资料。结果:就诊人群以青年患者多见,年龄在25～28岁,78.4%为轻、中度中毒,且21%～41%合并有饮酒史。极重度患者罕见,但死亡率极高。与轻、中度中毒相比,重度中毒患者就诊时间短,但治疗周期延长,有一定死亡风险。发病时间以春夏季为主,而且夜间0点至清晨8点为就诊高峰期。结论:急性苯丙胺中毒以年轻人多见,病情以轻、中度中毒为主,治疗时间较短,预后较好;重度、极重度患者病情恶化快,治疗周期长,死亡率高。
Objective: To observe the clinical features and therapeutic effects of acute amphetamines poisoning. Methods: A retrospective analysis of 88 cases of acute amphetamine poisoning in emergency department from January 2010 to June 2012 was performed. Results: Visiting patients were more common in young patients, ranging in age from 25 to 28 years. 78.4% were mild to moderate poisoning and 21% to 41% had alcohol consumption. Very rare patients are rare, but the mortality rate is extremely high. Compared with light and moderate poisoning, patients with severe poisoning have short treatment time, but the treatment cycle is prolonged and there is a certain risk of death. The onset time in spring and summer, and 0:00 to 8:00 in the morning for the peak treatment. Conclusions: Acute amphetamines are more common in young people, with mild to moderate poisoning, shorter treatment time and better prognosis. Patients in severe and severe cases are experiencing rapid deterioration, long treatment period and high mortality.