恶性肿瘤的瘤苗免疫治疗 ,是指应用肿瘤细胞或经各种基因修饰后的肿瘤细胞在体外制成瘤苗 ,经致死性剂量照射后 ,重新接种于患者体内 ,使逃避免疫监视的肿瘤细胞可以被免疫系统识别 ,从而诱导机体产生针对肿瘤细胞的主动的、特异性的免疫反应。目前 ,瘤苗免疫治疗已有很多成功的动物模型 ,人体的临床试验也取得了肯定的疗效。但如何进一步提高免疫效果 ,仍面临着许多问题和挑战 Malignant tumor vaccine immunotherapy refers to the application of tumor cells or a variety of gene modified tumor cells in vitro made of tumor vaccine irradiated by the lethal dose, re-vaccination in patients with immune cells to evade the tumor cells Can be recognized by the immune system to induce the body to produce an active, specific immune response against tumor cells. At present, tumor vaccine immunotherapy has many successful animal models, human clinical trials have also made a positive effect. However, there are still many problems and challenges in how to further improve the immunization effect