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目的分析HIV/AIDS患者结核菌素(PPD)反应及其与CD4细胞计数间的关系。方法采取前瞻性对照研究方法,对202名健康者及40例经免疫蛋白印迹法(WB)确证的HIV/AIDS病人进行PPD试验、CD4、CD8淋巴细胞计数。结果HIV/AIDS患者中PPD阳性率12.5%,健康对照PPD阳性率28.2%(P<0.05)。CD4细胞计数<200/mm3者,PPD均为阴性。CD4/CD8比值<1者达90%。结论HIV/AIDS患者机体免疫力降低,PPD反应明显下降。在确诊HIV/AIDS患者并发结核病时应值得注意。
Objective To analyze the relationship between tuberculin (PPD) reaction and CD4 cell count in HIV / AIDS patients. Methods A prospective controlled study was conducted to investigate PPD and CD4 and CD8 lymphocyte counts in 202 healthy individuals and 40 HIV / AIDS patients confirmed by Western blotting (WB). Results The positive rate of PPD was 12.5% in HIV / AIDS patients and 28.2% in healthy controls (P <0.05). CD4 cell count <200 / mm3, PPD were negative. CD4 / CD8 ratio of <1 were up to 90%. Conclusion The immunity of HIV / AIDS patients decreased and the PPD response decreased obviously. In the diagnosis of HIV / AIDS patients with tuberculosis should be noted.