目的观察无乳糖奶粉联合消旋卡多曲治疗婴幼儿急性水样腹泻的临床疗效。方法将120例年龄4～18个月,病程在1周内,以母乳或普通配方奶喂养为主的水样便腹泻患儿随机分为3组,A组:补液及对症治疗,口服思密达和双歧杆菌四联活菌片;B组:A组治疗+消旋卡多曲;C组:B组+无乳糖奶粉。A、B组继续母乳或普通配方奶喂养,C组改用无乳糖奶粉。观察疗效、粪便性状正常时间、止泻时间和住院天数。结果 B、C组患儿治疗总有效率优于A组(P均<0.05)。B组与C组之间差异有统计学意义(P<0.05)。3组患儿治疗后粪便性状正常时间、止泻时间和住院所需时间差异有统计学意义。B、C组均短于A组,C组短于B组(P<0.05)。结论无乳糖奶粉联合消旋卡多曲治疗婴幼儿急性水样腹泻可缩短病程,有效、安全。 Objective To observe the clinical efficacy of lactose-free milk powder combined with racecadotril in the treatment of infantile acute watery diarrhea. Methods A total of 120 children aged 4-18 months with a course of 1 week were randomly divided into three groups according to the watery sample diarrhea fed with breast milk or common formula. Group A: fluid replacement and symptomatic treatment, oral Smeic Bifidobacterium and Bifidobacterium quadriceps; B group: A treatment + racecadotril; C group: B group + lactose-free milk powder. A, B continue to breast milk or normal formula feeding, C group switched to lactose-free milk powder. Observed efficacy, normal stool, diarrhea and hospitalization days. Results The total effective rate of treatment in children in groups B and C was better than that in group A (all P <0.05). The difference between group B and group C was statistically significant (P <0.05). There was significant difference in the normal time of defecation, diarrhea time and hospitalization time between the three groups. B and C groups were shorter than A group, C group was shorter than B group (P <0.05). Conclusion No lactose milk powder combined with racecadotril treatment of acute watery diarrhea in infants and young children can shorten the course, effective and safe.