论文部分内容阅读
据瑞士巴塞尔大学Mihatsch等报道:他们通过25年约35,000例尸检的回顾性研究发现,非滥用药者的泌尿肿瘤发生率是1.27%,滥用非那西丁者的泌尿道肿瘤发生率是8.6%。其他研究也表明,有6～12%的非那西丁滥用者发生了泌尿道肿瘤。在近期的活组织检查研究中发现了类似的倾向,其中只包括侵润性泌尿道肿瘤。根据两项研究的结果,得出的结论是:非那西丁滥用者泌尿道肿瘤的发生率是非滥用药者的8.5～13倍。非滥用镇痛药者中的肿瘤发生部位差异很大。例
According to a review by Mihatsch et al. At the University of Basel in Switzerland, they found that the incidence of urological tumors in non-abusers was 1.27% through a retrospective study of 35,000 autopsies in 25 years. The incidence of urinary tract tumors in those who abused phenacetin was 8.6 %. Other studies have also shown that urinary tract tumors occur in 6-12% of phenacetin abusers. A similar trend was found in recent biopsy studies, including invasive urinary tract tumors. Based on the results of the two studies, it was concluded that the incidence of urinary tract tumors among non-abusers of phenacetin was 8.5 to 13 times higher than those who did not abuse drugs. There is a wide range of tumorigenic sites in non-abuse analgesics. example