1906年巴塞尔(瑞士)大学的Alfred Vogt报告一种有两眼虹膜——睫状体炎,秃发或者有头发、眉毛、睫毛等灰变(Poliosis)的疾病。1914年,1929年日本小柳美三对同样疾病作了详细描述。即两眼严重弥漫性葡萄膜炎,常伴视网膜剥禽,除毛发改变外,还有皮肤白斑、耳聋等的综合征,从此,有Vogt—小柳(Koyanagi)综合征之名称,1926年日本原田永之助报告了一种两眼急性弥漫性脉络膜炎,伴有严 Alfred Vogt of the University of Basel (Switzerland) in 1906 reported a condition with two irises - ciliary body inflammation, alopecia or poliosis with hair, eyebrows and eyelashes. In 1914, Japan’s Komeito in 1929 made a detailed description of the same disease. That is, two eyes with severe diffuse uveitis, often accompanied by retinal stripping of poultry, in addition to hair changes, there are skin white spots, deafness syndrome, since then, the name of Vogt-Koyanagi syndrome, 1926 Japan Harada Yongzhi Acute diffuse choroiditis of both eyes was reported, accompanied by stricture