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测定30例吸烟母亲的新生儿和60例不吸烟母亲的新生儿脐带血中前清蛋白、清蛋白、甘油三酯、葡萄糖、胰岛素、胰岛素样生长因子1、胰岛素样生长因子结合蛋白3、pH值、乳酸、红细胞生成素和血红蛋白浓度。结果显示,吸烟母亲的婴儿出生时体重、身长和头围均明显低于对照组,胰岛素、胰岛素样生长因子1、胰岛素样生长因子结合蛋白3浓度也明显低于对照组,血红蛋白和红细胞生成素显著高于对照组,血pH值和乳酸浓度无差别,前清蛋白、清蛋白、甘油三酯和葡萄糖浓度无明显差异。妊娠期吸烟导致胎儿匀称的生长减慢,可能是由于输送给胎儿的氧减少,胎儿的胰岛素、胰岛素样生长因子1和胰岛素样生长因子结合蛋白3浓度降低所致。
Determination of pre-albumin, albumin, triglycerides, glucose, insulin, insulin-like growth factor 1, insulin-like growth factor binding protein 3 in umbilical cord blood of 30 newborns with smoking mothers and 60 non-smoking mothers Value, lactic acid, erythropoietin and hemoglobin concentration. The results showed that the weight, length and head circumference of the smoking mothers’ infants were significantly lower than those of the control group. The concentrations of insulin, insulin-like growth factor 1 and insulin-like growth factor binding protein 3 were also significantly lower than those of the control group. The hemoglobin and erythropoietin Was significantly higher than the control group, no difference in blood pH and lactate concentration, prealbumin, albumin, triglyceride and glucose concentration was no significant difference. Smoking during pregnancy leads to a slowing of the symmetrical growth of the fetus, possibly due to reduced oxygen delivered to the fetus, reduced levels of fetal insulin, insulin-like growth factor 1 and insulin-like growth factor binding protein 3.