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异位妊娠是妇产科常见的急腹症,近二十年发病率呈上升趋势,提高诊断技术可减少异位妊娠误诊率及漏诊率,为保守治疗及保留输卵管的再生育功能创造有利条件。目前异位妊娠早期诊断主要依靠超声和血清人绒毛膜促性腺激素β亚单位(β-hCG)化验检查,但在妊娠4～5周时,尚不能完全确定妊娠部位。近年用于诊断异位妊娠的血清标志物的研究有一定进展,就有关异位妊娠早期诊断的血清标志物——血清hCG、孕激素、血管内皮生长因子、妊娠相关血浆蛋白、激活素-抑制素的研究进展做文献综述。
Ectopic pregnancy is a common acute abdomen in obstetrics and gynecology, the incidence of the past 20 years is on the rise, to improve diagnostic techniques can reduce the misdiagnosis rate and misdiagnosis rate of ectopic pregnancy, to create favorable conditions for conservative treatment and retention of reproductive function of fallopian tubes . At present, the diagnosis of ectopic pregnancy depends mainly on the ultrasound and serum human chorionic gonadotropin beta subunit (β-hCG) test, but at 4 to 5 weeks of pregnancy, the pregnancy site can not be completely determined yet. In recent years, there has been some progress in the study of serum markers for the diagnosis of ectopic pregnancy. Serum markers of early diagnosis of ectopic pregnancy such as serum hCG, progesterone, vascular endothelial growth factor, pregnancy-associated plasma proteins, activin-inhibition Literature review of the literature review.