以抗杜庆利什曼单克隆抗体L_(12)F_7检测黑热病病人的循环抗原。文中对1986～1989年收集并低温保存的118份血清加以检测,阳性率为88.9％;另检测经锑剂治疗后的患者血清57份,结果均为阴性。同时又以IFA检测体内抗体,阳性率为68.4％。这57例治愈者经追踪观察并未出现复发及抗锑现象。因而用单克隆抗体检测循环抗原的另一优越性,可以作为疗效考核的新方法。 Anti-Du Qing Leishman monoclonal antibody L_ (12) F_7 detection of kala-azar patient’s circulating antigen. In this paper, 118 sera collected from 1986 to 1989 and stored at low temperature were detected with a positive rate of 88.9%. In addition, 57 serum samples from patients treated with antimony agent were negative. At the same time IFA detection of in vivo antibodies, the positive rate was 68.4%. The 57 healers were followed up and found no relapse and anti-antimony phenomenon. Therefore, the use of monoclonal antibodies to detect another advantage of circulating antigens, can be used as a new method of assessment of efficacy.