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目的探讨丙泊酚联合芬太尼应用于人工流产术中镇痛的临床效果。方法选取2014—2015年某院收治的行无痛人流术患者1500例,随机分为A组、B组与C组,各500例。A组给予宫术宁棒镇痛,B组给予利多卡因宫颈局部注射镇痛,C组给予丙泊酚联合芬太尼镇痛。观察3组患者的镇痛效果、人工流产综合征发生情况、麻醉时间以及宫颈口松弛状况。结果 C组患者总有效率高于A组、B组,差异有统计学意义(P<0.05);3组患者扩宫率比较,差异无统计学意义(P>0.05);C组患者麻醉起效时间短于A组、B组,差异有统计学意义(P<0.05);C组患者麻醉维持时间长于A组、B组,差异有统计学意义(P<0.05);3组患者人工流产综合征发生率比较,差异无统计学意义(P>0.05)。结论丙泊酚联合芬太尼应用于人工流产术镇痛的效果显著,且并发症少。
Objective To investigate the clinical effect of propofol combined with fentanyl on analgesia induced by induced abortion. Methods A total of 1500 patients with painless abortion admitted in a hospital from 2014 to 2015 were randomly divided into A group, B group and C group, each with 500 cases. Group A was given moxibustion Ning Bang analgesic, group B was given local injection of lidocaine cervical pain, group C was given propofol combined with fentanyl analgesia. The analgesic effect, the incidence of induced abortion syndrome, the time of anesthesia and the cervix relaxation were observed in the three groups. Results The total effective rate of group C was higher than that of group A and group B (P <0.05). There was no significant difference between the three groups in the rate of expansion (P> 0.05) (P <0.05). The duration of anesthesia maintenance in group C was longer than that in group A and group B (P <0.05). The abortion in three groups was statistically significant The incidence of syndromes, the difference was not statistically significant (P> 0.05). Conclusion Propofol combined with fentanyl for abortion analgesic effect is significant, and less complications.