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目的 观察金荞麦有效部位Fr4对荷瘤小鼠的抗肿瘤作用。方法 采用荷瘤小鼠模型 ,口服金荞麦Fr47d后 ,观察其对肉瘤S180、肝癌H2 2实体瘤的抑制作用及对S180腹水瘤的生命延长作用 ,并观察其对荷瘤小鼠免疫效应指标的影响。结果 Fr4对肉瘤S180、肝癌H2 2实体瘤抑制率为 41.4%～ 6 8.3%。Fr4对S180腹水型小鼠生命延长率无明显变化。结论 金荞麦Fr4可抑制S180肉瘤、肝癌H2 2实体瘤的生长 ,对荷瘤小鼠免疫机能无改善及抑制作用
Objective To observe the anti-tumor effect of Fr4, an effective fraction from Fagopyrum quinquefolius, on tumor-bearing mice. Methods The tumor-bearing mice model was used to observe the inhibitory effect of oral quinoa Fr47d on sarcoma S180, H2 2 solid tumor of hepatocellular carcinoma and life prolongation of S180 ascites tumor, and observe its immune effect on tumor-bearing mice. influences. Results The inhibitory rate of Fr4 on sarcoma S180 and hepatocellular carcinoma H2 2 solid tumors was 41.4% to 68.3%. Fr4 had no significant change in the life extension rate of S180 ascitic mice. Conclusion Fr4 of golden buckwheat can inhibit the growth of S180 sarcoma and H2 2 solid tumor of hepatocellular carcinoma, and it has no effect on immune function and inhibition of tumor-bearing mice.