分子影像学是在分子和细胞水平对人或其他活体的生物学过程进行可视化、特征化和监测的科学[1],其迅速发展使疾病诊断由传统的解剖形态学向功能、代谢、受体和基因的分子水平转化。核医学作为最成熟的分子影像技术,其所用设备也从单模态发展到双模态,其中单光子发射计算机断层成像术(single-photon emission computed tomography,SPECT)/CT融合骨显像在骨骼系统疾病的诊治 Molecular imaging is a science that visualizes, characterizes, and monitors the biological processes in humans and other living organisms at the molecular and cellular level [1], and its rapid development has led to the identification of diseases from traditional anatomical morphology to functional, metabolic, And the molecular level of gene transformation. As the most mature molecular imaging technique, nuclear medicine has been developed from single modality to dual modality. Single-photon emission computed tomography (SPECT) / CT fusion bone imaging System disease diagnosis and treatment