论文部分内容阅读
假性甲状旁腺机能减退症(PHP)是具有甲状腺机能减退症(HPT)的特征(低血钙、高血磷,尿钙、磷降低,手足抽搦等)。但血PTH高于正常,周围靶组织对PTH生物活性不敏感,甲状旁腺可以增生肥大,常伴有先天性发育畸形的一类综合征。该病最先由Albright报道,1979年Aurbach统计世界资料约为100例,近年报告日渐增多,国内也有报告,对其发病机理和临床类型也有一些研究。
Pseudo-hypoparathyroidism (PHP) is a hallmark of hypothyroidism (HPT) (hypocalcemia, hyperphosphatemia, urinary calcium, phosphorus reduction, hand-foot pump, etc.). However, blood PTH is higher than normal, the surrounding target tissue is not sensitive to biological activity of PTH, hyperplasia of hypertrophy of the parathyroid gland, often accompanied by congenital malformations of a class of syndrome. The disease was first reported by Albright. In 1979, the Aurbach statistical world data was about 100 cases. The reports in recent years have been increasing. There are also reports in China. There are also some studies on its pathogenesis and clinical types.