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目的通过对493份药品不良反应(ADR)报告的分析,为临床合理用药提供依据。方法对493例ADR病例,按患者年龄、性别、给药途径,使用药品分类及临床表现等进行分析。结果抗感染药物引起的不良反应居首位(占66.13%),其次为中药制剂(占23.94%)。给药途径以静脉滴注为主(占81.14%)。结论临床医师与药师在患者使用药物之后要加强ADR监测,确保安全有效地用药。
OBJECTIVE: To provide a basis for clinical rational drug use through the analysis of 493 reports of adverse drug reactions (ADRs). Methods 493 cases of ADR were analyzed according to patient’s age, sex, route of administration, classification of drug use and clinical manifestations. Results Anti-infectives caused the most adverse reactions (66.13%), followed by traditional Chinese medicine preparations (23.94%). The main route of administration to intravenous drip (81.14%). Conclusion Clinicians and pharmacists need to step up ADR monitoring after their patients have taken medications to ensure safe and effective medication.