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近些年来,人们采用酶联免疫吸附试验法(ELISA)及最近开展的流式细胞测定法(Flow Cytometric Method,FCM)对可溶性白细胞介素2受体(SIL-2R)作了大量的临床研究,提示了SIL-2R在一些疾病中具有辅助诊断、观察病情变化和疗效及判断预后的重要参考价值。(一)恶性肿瘤毛细胞性白血病患者SIL-2R明显增高,当治疗有效、临床情况好转后SIL-2R下降,反之,病情加重或复发则SIL-2R又随之上升。何杰金病治疗前血清SIL-2R明显增高,
In recent years, a large number of clinical studies on soluble interleukin 2 receptor (SIL-2R) have been performed using enzyme-linked immunosorbent assay (ELISA) and recently introduced flow cytometry (FCM) , Suggesting that SIL-2R in some diseases with auxiliary diagnosis, observation of disease changes and efficacy and prognosis of the important reference value. (A) SIL-2R was significantly increased in patients with malignant tumor of hairy cell leukemia, SIL-2R decreased when the clinical condition improved after the treatment was effective. Conversely, the SIL-2R increased with the exacerbation or recurrence. Hodgkin’s disease before treatment serum SIL-2R was significantly higher,