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目的：回顾本院近３年来伽玛刀治疗脑转移瘤的情况，阐明其治疗的有效性，研究影响患者预后的相关因素。方法：回顾性调查１９９３年１０月～１９９５年１１月治疗的１５３例脑转移瘤患者（３７２个病灶）。平均年龄为５７岁，平均卡氏评分６７％，平均随访时间２４个月。通过Ｃｏｘ多元回归分析影响生存时间的１３个因素。统计学上有显著的差异Ｐ＜０．０５。结果：术后平均生存时间为８．５个月。多元统计分析原发肿瘤稳定，卡氏评分大于７０％，病灶３个或更少以及全身化疗加原发肿瘤切除这四个因素能明显延长生存时间（Ｐ＜０．０５），由此引入一个五级评分系统来预测患者的生存时间（每个因素为１分，分别为４，３，２，１，０分）。４分患者有１２个月存活时间，３分１０个月，２分６个月，１分３个月，０分１个月。结论：伽玛刀是一种安全有效适用于中、小体积，等级评分大于１分的脑转移瘤患者的治疗方法
OBJECTIVE: To review the treatment of brain metastases with Gamma Knife in the past 3 years in our hospital, to clarify the effectiveness of its treatment and to study the related factors that affect the prognosis of patients. Methods: 153 patients with brain metastases (372 lesions) treated from October 1993 to November 1995 were retrospectively reviewed. The average age was 57 years old, with an average Karnofsky score of 67%. The average follow-up time was 24 months. Cox multivariate regression analysis of 13 factors that affect survival time. There was a statistically significant difference P <0.05. Results: The average postoperative survival time was 8.5 months. Multivariate statistical analysis of the primary tumor was stable, with a Karnofsky scale score greater than 70%, and lesions of 3 or fewer as well as systemic chemotherapy plus primary tumor resection, which significantly prolonged survival (P <0.05), thereby introducing a Five-point scoring system to predict patient survival time (1 point for each factor, 4, 4, 2, 1, 0, respectively). 4 patients have a 12-month survival time, 3 minutes and 10 months, 2 minutes and 6 months, 1 minute and 3 months, 0 minutes and 1 month. Conclusion: Gamma Knife is a safe and effective treatment for patients with metastatic brain tumors of medium and small size with a grade score greater than 1