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目的 分析影响维持性血液透析患者感染丙型肝炎的危险因素。方法 收集 12 0例血透患者的临床资料 ,采用第二代 EL ISA法检测血抗 - HCV;临床资料包括 :年龄、性别、血透时间、每周透析时间、输血和血制品史和量、合并 HBV感染、肾脏移植史、CAPD史、AL T异常史、肝炎史、结核史以及医院感染史等。结果 单因素分析表明 HCV感染与透析时间、每周透析时间、输血、血制品史和量、肾移植史、医院感染史、AL T增高史显著性相关 ;L ogistic逐步回归分析证实 HCV感染的原因为输血和医源性传播。结论 结果提示要采取严格的预防措施 ,减少输血和隔离抗 - HCV阳性患者 ,对控制 HCV感染意义重大。
Objective To analyze the risk factors affecting Hepatitis C infection in maintenance hemodialysis patients. Methods The clinical data of 120 patients with hemodialysis were collected and the blood anti-HCV was detected by the second generation ELISA. The clinical data included age, sex, hemodialysis time, dialysis time per week, history of blood transfusion and blood products, Combined HBV infection, kidney transplantation history, CAPD history, AL T abnormal history, history of hepatitis, tuberculosis and history of hospital infection. Results Univariate analysis showed that HCV infection was significantly associated with dialysis time, dialysis time per week, blood transfusion, history of blood products, renal transplant history, nosocomial infection and elevated ALT; L ogistic stepwise regression analysis confirmed the cause of HCV infection For blood transfusion and iatrogenic transmission. Conclusions The results suggest that strict precautions should be taken to reduce blood transfusions and isolation of anti-HCV-positive patients, with significant implications for the control of HCV infection.