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目的旨在了解小儿Ⅰ型糖尿病酮症酸中毒（ＤＫＡ）时血乳酸水平的变化。方法１９９６年２月～１９９７年１２月对天津儿童医院内分泌科住院的２５例ＤＫＡ患者进行血乳酸水平的临床观察。结果Ⅰ型ＤＭ在发生ＤＫＡ时仍可以发生乳酸酸中毒，其发生率为４％。结论ＤＫＡ时血乳酸可升高，并可发生乳酸性酸中毒，其血乳酸水平与血糖、尿糖、酮体尿、ｐＨ值、ＢＥ变化无相关性。在充分的病因、对症治疗和积极的胰岛素治疗，ＤＫＡ恢复后乳酸可逐渐下降，以至恢复正常，不需特殊治疗。
The purpose is to understand the changes of blood lactic acid in children with type 1 diabetic ketoacidosis (DKA). Methods From February 1996 to December 1997, 25 cases of DKA hospitalized in Department of Endocrinology, Tianjin Children’s Hospital were enrolled in the study. Results Type 1 DM lactic acidosis can occur in the occurrence of DKA, the incidence was 4%. Conclusions Lactate acidosis may occur in DKA, and there is no correlation between blood lactic acid level and blood sugar, urine sugar, ketone body urine, pH and BE. In the full etiology, symptomatic treatment and active insulin treatment, lactic acid can gradually decline after DKA recovery, and even returned to normal, without special treatment.